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GLP-1 drug pipelines

The complete GLP-1 pipeline — approved, Phase 3, and next-gen.

Semaglutide, tirzepatide, retatrutide, oral GLP-1s, and dual/triple incretin agonists. Track sponsor companies, ongoing trials, and upcoming FDA catalysts.

Last updated:Jul 15, 2026Source:ClinicalTrials.gov, FDA.gov, company IRVerified:Manually reviewed by PeptidePlanet research teamData provider:PeptidePlanet Research

Approved & investigational

Every material GLP-1 program from Novo, Lilly, Viking, Structure, Altimmune, and Amgen.

Trial-level detail

NCT identifiers, phase, sponsor, primary completion dates, and outcome measures.

Catalyst calendar

PDUFA dates, expected data readouts, and label expansions in one view.

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Frequently asked questions

What are GLP-1 drugs?
GLP-1 receptor agonists mimic the incretin hormone glucagon-like peptide-1 to improve glycemic control and induce satiety. Approved examples include semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 agonist.
Which companies are leading the GLP-1 pipeline?
Novo Nordisk and Eli Lilly dominate today. Viking Therapeutics, Structure Therapeutics, Altimmune, and Amgen have late-stage or notable early-stage next-generation candidates including oral GLP-1s and multi-agonists.
What is retatrutide?
Retatrutide is Eli Lilly's investigational triple agonist targeting GLP-1, GIP, and glucagon receptors, currently in Phase 3 trials for obesity and related indications.
How often is the GLP-1 tracker updated?
Pipeline entries are reviewed weekly against ClinicalTrials.gov and company IR releases. Every peptide profile shows a last-updated date and links to primary sources.
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